|   23 نوفمبر 2024م
Dr. Adel Ehab Ibrahim
Dr. Adel Ehab Ibrahim
Assistant Professor
Pharmaceutical Chemistry and Instrumental Analysis...
مركز أبحاث العلوم الطبيعية والطبية
  • هاتف: 25446200(968+)
  • محول: 802
  • البريد الإلكتروني: adel@unizwa.edu.om
  • موقع المكتب: 25B G06...
  • يعمل في الجامعة: منذ 2022
  • الحالة الاجتماعية: ....



  • المؤهلات الأكاديمية
    • M.Sc. in Quality Management، The Arab Academy for Science, Technology and Maritime Transport, Egypt، 2023
    • Ph.D. in Pharmaceutical Analytical Chemistry، Faculty of Pharmacy, Zagazig University, Egypt، 2018
    • M.Sc. in Pharmaceutical Chemistry، Faculty of Pharmacy, Zagazig University, Egypt.، 2012
    • B.S. Pharmacy، Faculty of Pharmacy, Alexandria University, Egypt، 2004
      الأنشطة البحثية
            - المنشورات
              مقال:
            • 1. 2024 Leveraging Strengths of Green Chromatography in Developing Eco-friendly HPLC and HPTLC Methods for the Simultaneous Analysis of Lamivudine, Dolutegravir and Tenofovir alafenamide، Microchemical Journal, 207 (2024) 111645
            • 2. 2024 Independent concentration extraction as a novel green approach resolving overlapped UV–Vis binary spectra and HPTLC-densitometric methods for concurrent determination of levocloperastine and chlorpheniramine، BMC Chemistry 18, (2024) 160.
            • 3. 2024 Copper and Nitrogen-doped Carbon Quantum Dots as Green Nano-Probes for Fluorimetric Determination of Delafloxacin; Characterization and Applications، Analytica Chimica Acta (2024): 343175
            • 4. 2024 Investigating Trace and Macro-element Composition of Herbal and Nutraceutical Dietary Supplements Marketed in Oman: Insights into Safety and Labeling، Biological Trace Element Research, (2024); DOI: 10.1007/s12011-024-04343-w
            • 5. 2024 Design, Characterization and Biopharmaceutical Applications of Novel Green Boron-Carbon Quantum Dots for Quantification of Apalutamide; Greenness Evaluations، Journal of Fluorescence, (2024) https://doi.org/10.1007/s10895-024-03802-w.
            • 6. 2024 The Promising Effect of Ascorbic Acid and Paracetamol as Anti-Biofilm and Anti-Virulence Agents against Resistant Escherichia coli، Current Issues in Molecular Biology, 46 (2024) 6805-6819.
            • 7. 2024 Synthesis of organic solvent-free nitrogen-doped carbon quantum dots as unique green fluorimetric probes for analysis of abrocitinib in human plasma، Luminescence, 39 (2024) e4801.
            • 8. 2024 Polypogon monspeliensis Hepatoprotective Attributes: UHPLC/ QTOF-MS/MS Metabolite Profiling and In Vitro and In Silico Studies، Revista Brasileira de Farmacognosia, (2024). https://doi.org/10.1007/s43450-024-00554-3
            • 9. 2024 Verapamil-Loaded Cubosomes for Enhancing Intranasal Drug Delivery: Development, Characterization, Ex Vivo Permeation, and Brain Biodistribution Studies، AAPS PharmSciTech, 25 (2024) 95.
            • 10. 2024 Tracking the Variations in Trace and Heavy Elements in Smoking Products Marketed in Oman and Egypt: Risk Assessment After Implementation of Constraining Protocols، Biological Trace Element Research, (2024). https://doi.org/10.1007/s12011-024-04182-9
            • 11. 2024 A new green fluorimetric micelle complexation approach for reduction of the consumed solvent and quantification of avapritinib in biological fluids، RSC advances, 14 (2024) 10445-10451
            • 12. 2024 Optimization and characterization of quercetin-loaded solid lipid nanoparticles for biomedical application in colorectal cancer، Cancer Nanotechnology, 15 (2024) 16
            • 13. 2024 Design, Characterization, and Bioanalytical Applications of Green Terbium-and Nitrogen-Doped Carbon Quantum Dots as a Fluorescent Nanoprobe for Omadacycline Analysis، Applied Spectroscopy, 78 (2024) 329-339.
            • 14. 2023 Novel green HPTLC and organic solvent-free micellar LC methods for the simultaneous determination of Ozenoxacin and benzoic acid; greenness assessment and applications، Sustainable Chemistry and Pharmacy, 36 (2023) 101277
            • 15. 2023 Integrating micellar HPLC and green analytical chemistry tools in greenness assessment of five commonly Co-formulated antidiabetic drugs، Sustainable Chemistry and Pharmacy, 35 (2023) 101199.
            • 16. 2023 Fast and Sensitive Bioanalytical Method for the Determination of Deucravacitinib in Human Plasma Using HPLC-MS/MS: Application and Greenness Evaluation، Molecules, 28 (2023) 5471.
            • 17. 2023 Recent Advances in Chiral Selectors Immobilization and Chiral Mobile Phase Additives in Liquid Chromatographic Enantio-separations; A Review، Journal of Chromatography A, 1706 (2023) 464214.
            • 18. 2023 Development of cysteine-doped MnO2 quantum dots for spectrofluorimetric estimation of copper: applications in different matrices، Analytical and Bioanalytical Chemistry, 415 (2023) 5529-5538.
            • 19. 2023 Preparation, Characterization and Application of a Novel Selective Mercury Electrode Using Natural Epoxide as a Green Anion Carrier، Microchemical Journal, 192 (2023) 108905
            • 20. 2023 Studying molecular interactions via capillary electrophoresis and microscale thermophoresis: A review، Electrophoresis, 44 (2023) 1114–1142
            • 21. 2023 Evaluation of Biofloc-Based Probiotic Isolates on Growth Performance and Physiological Responses in Litopenaeus vannamei، Water 2023, 15(16), 3010
            • 22. 2023 Zinc(II) complexation strategy for ultra-sensitive fluorimetric estimation of molnupiravir: Applications and greenness evaluation، Archiv der Pharmazie, 356 (2023) 2300005
            • 23. 2023 Toxic Elemental Impurities in Herbal Weight Loss Supplements; A Study Using ICP-OES Microwave-Assisted Digestion، Toxics, 11 (2023) 272
            • 24. 2023 An Innovative Polymer-Based Electrochemical Sensor Encrusted with Tb Nanoparticles for the Detection of Favipiravir: A Potential Antiviral Drug for the Treatment of COVID-19، Biosensors, 13 (2023) 243
            • 25. 2023 Comparative Evaluation of Reversed Stationary Phase Geometries and Greener Systems on HPLC and UHPLC Using Five Recent Hepatitis-C Antivirals، Journal of AOAC International, 106 (2023) 580-587.
            • 26. 2023 Green Chemometric Determination of Cefotaxime Sodium in the Presence of Its Degradation Impurities Using Different Multivariate Data Processing Tools; GAPI and AGREE Greenness Evaluation، Molecules, 28 (2023) 2187
            • 27. 2023 Phytochemical Characterization of Pterocephalus frutescens with In-Silico Evaluation as Chemotherapeutic Medicine and Oral Pharmacokinetics Prediction Study، Scientia Pharmaceutica, 91 (2023) 7.
            • 28. 2023 Determination of Sodium, Potassium, and Magnesium as Sulfate Salts in Oral Preparations Using Ion Chromatography and Conductivity Detection، Separations, 10 (2023) 99
            • 29. 2023 Micellar Organic-solvent Free HPLC Design of Experiment for the Determination of Ertapenem and Meropenem; Assessment using GAPI, AGREE and Analytical Eco-scale models، Microchemical Journal, 185 (2023) 108262
            • 30. 2022 Antitrypanosomal, Antitopoisomerase-I, and Cytotoxic Biological Evaluation of Some African Plants Belonging to Crassulaceae; Chemical Profiling of Extract Using UHPLC/QTOF-MS/MS، Molecules, 27 (2022) 8809
            • 31. 2022 Dinebra retroflexa Herbal Phytotherapy: A Simulation Study Based on Bleomycin-Induced Pulmonary Fibrosis Retraction Potential in Swiss Albino Rats، Medicina 58 (2022) 1719
            • 32. 2022 Design of an Experimental Study for the Simultaneous Determination of Cefepime, Piperacillin and Tazobactam Using Micellar Organic Solvent-Free HPLC، Separations, 9 (2022) 215
            • 33. 2022 Microscale thermophoresis as a powerful growing analytical technique for the investigation of biomolecular interaction and the determination of binding parameters، Methods and Applications in Fluorescence, 10 (2022) 042001.
            • 34. 2022 Bimodal Release Two-In-One Clonazepam Matrix Lozenge Tablets for Managing Anxiety-Related Disorders: Formulation, Optimization and In-Vivo Evaluation، Scientia Pharmaceutica, 90 (2022) 43.
            • 35. 2022 Microscale Thermophoresis and Molecular Modelling to Explore the Chelating Drug Transportation in the Milk to Infant، Molecules, 27 (2022) 4604
            • 36. 2022 Highly sensitive high-performance thin-layer chromatography method for the simultaneous determination of Molnupiravir, Favipiravir, and Ritonavir in pure forms and pharmaceutical formulations، Journal of Separation Science, 45 (2022) 2582-2590
            • 37. 2022 Analytical Performance and Greenness Evaluation of Five Multi-Level Design Models Utilized for Impurity Profiling of Favipiravir, a Promising COVID-19 Antiviral Drug، Molecules, 27 (2022) 3658.
            • 38. 2022 Fabrication of novel quantum dots for the estimation of COVID-19 antiviral drug using green chemistry: application to real human plasma، RSC Advances, 12 (2022) 16624–16631
            • 39. 2022 Cost-effective, Green HPLC Determination of Losartan, Valsartan and their Nitrosodiethylamine Impurity; Application to Pharmaceutical Dosage-forms، Royal Society Open Science, 9 (2022) 220250.
            • 40. 2022 Two Green Micellar HPLC and Mathematically Assisted UV Spectroscopic Methods for the Simultaneous Determination of Molnupiravir and Favipiravir as a Novel Combined COVID-19 Antiviral Regimen، Molecules, 27 (2022) 2330
            • 41. 2022 Eco-Friendly and Sensitive HPLC and TLC Methods Validated for the Determination of Betahistine in the Presence of Its Process-Related Impurity، Separations, 9 (2022) 49
            • 42. 2022 Validated Capillary Zone Electrophoresis Method for Impurity Profiling and Determination of NiII (3-OMe-Salophene)، Separations, 9 (2022) 25
            • 43. 2021 Green Stability Indicating Organic Solvent-Free HPLC Determination of Remdesivir in Substances and Pharmaceutical Dosage Forms، Separations, 8 (2021) 243
            • 44. 2021 Determination of six drugs used for treatment of common cold by micellar liquid chromatography، Analytical and Bioanalytical Chemistry, 413 (2021) 5051-5056.
            • 45. 2021 Erectile Dysfunction and Premature Ejaculation Drugs: Mode of Action and Analytical Methods Literature Review، Journal of Drug Research and Development, 7 (2021) 1-7
            • 46. 2021 Overview on liquid chromatography and its greener chemistry application، Annals of Advances in Chemistry, 5 (2021) 04-12
            • 47. 2021 Green Sensitive Spectrofluorimetric determination of Remdesvir, an FDA approved SARS-COV-2 Candidate Antiviral; Application in Pharmaceutical Dosage Forms and Spiked Human Plasma، Analytical methods, 13 (2021) 2596-2602
            • 48. 2021 Overview on Hepatitis C, Treatment Strategy, Instrumental Analysis of Anti-HCV drugs، Journal of Pharmacy and Drug Innovations, 2 (2021), DOI: http;//doi.org/03.2020/1.1014.
            • 49. 2021 Mini review on Chromatography of Proteomics، Global Journal of Chemical Sciences, 1 (2021) 1-4.
            • 50. 2021 Green micellar solvent-free HPLC and Spectrofluorimetric determination of Favipiravir as one of COVID-19 antiviral regimens، Microchemical Journal, 165 (2021) 106189.
            • 51. 2021 Chemometry-assisted UV-spectrophotmetric methods forthe simultaneous determination of paritaprevir, ritonavir, and ombitasvir in their combined tablet dosage forms: A comparative study، Journal of Chemometrics, 35 (2021) e3339
            • 52. 2021 Validation of HPLC-UV Multi-Residue Method for the Simultaneous Determination of Tetracycline, Oxytetracycline, Spiramycin and Neospiramycin in Raw Milk، Food Analytical Methods, 14 (2021) 36-43.
            • 53. 2021 An eco-friendly micellar HPLC method for the simultaneous determination of triamtrene and xipamide in active pharmaceutical ingredients and marketed tablet dosage form، Acta Chromatographica, 33 (2021) 51-56.
            • 54. 2020 Solvent-free mixed micellar mobile phases; an advanced green chemistry approach for reversed phase HPLC determination of some antihypertensive drugs، Journal of Separation Science, 43 (2020) 3224-3232.
            • 55. 2020 Development and validation of eco-friendly micellar HPLC method for the simultaneous determination of hydrochlorothiazide and valsartan in bulk powder and pharmaceutical dosage forms، Journal of Iranian Chemical Society, 17 (2020) 1725-1730
            • 56. 2020 Monolithic and core-shell particles stationary phase morphologies in protein analysis; Peptide mapping of erythropoietin hormone and determination of carbetocin، Annales Pharmaceutique Francaises, 78 (2020) 206-216.
            • 57. 2020 Core–shell particles and monolithic columns; tools for simultaneous LC analysis of avanafil, sildenafil, apomorphine, trazodone, yohimbine, tramadol and dapoxetine in pharmaceutical dosage forms, counterfeit products and human plasma، RSC advances 10 (2020) 1379-1387.
            • 58. 2019 Assessment and validation of green stability indicating RP-HPLC method for simultaneous determination of timolol and latanoprost in pharmaceutical dosage forms using eco-friendly chiral mobile phase، Microchemical Journal, 148 (2019) 21-26.
            • 59. 2019 Development and validation of eco-friendly micellar-HPLC and HPTLC-densitometry methods for the simultaneous determination of paritaprevir, ritonavir and ombitasvir in pharmaceutical dosage forms، Heliyon, 5 (2019) e01518
            • 60. 2018 Performance Comparison Between Monolithic, Core-Shell, and Totally Porous Particulate Columns for Application in Greener and Faster Chromatography، Journal of AOAC International, 101 (2018)1985-1992.
            • 61. 2017 A rapid stability indicating LC-method for determination of Praziquantel in presence of its pharmacopoeial impurities، Arabian Journal of chemistry, 10 (2017) S35-S41
            • 62. 2016 Simultaneous determination of the antihypertensives hydrochlorothiazide, losartan potassium, irbesartan and valsartan in bulk powders and pharmaceutical preparations by HPLC، Main Group Chemistry, 15 (2016) 335-346.
            • 63. 2015 A novel stability indicating HPLC-method for simultaneous determination of atenolol and nifedipine in presence of atenolol pharmacopeoial impurities، Journal of Applied Pharmaceutical Science, 5 (2015) 017-025.
            • 64. 2014 Chromatographic analysis of some drugs employed in erectile dysfunction therapy: Qualitative and quantitative studies using calixarene stationary phase، Journal of Separation Science 37 (2014) 2814-2824.
            • 65. 2014 Comparison between Calixarene and conventional HPLC-phases concerning with separation of antihypertensive drugs، Journal of Liquid Chromatography & Related Technologies, 37 (2014) 1-25.
                الأنشطة الاستشارية
                • Pharmaceutical Quality Consultant، OTC Pharma, Sabaa Pharm، Egypt، 2019- 2021
                • Pharmaceutical Quality Control Manager، GYPTO Pharma، Egypt، 2020- 2021
                العضوية في الهيئات المهنية
                • 2023-الآن: Society for Applied Spectroscopy, USA
                • 2004-الآن: Egyptian Pharmacy Syndicate

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